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ea0056oc1.3 | Benign thyroid diseases | ECE2018

Thyroid hormone replacement therapy for subclinical hypothyroidism in adults: systematic review and meta-analysis of randomized-controlled trials

Snel Marieke , Feller Martin , Moutzouri Elisavet , Ford Ian , Gussekloo Jacobijn , Kearney Patricia , Mooijaart Simon , Quinn Terry , Aujesky Drahomir , Stott David , Westendorp Rudi , Rodondi Nicolas , Dekkers Olaf

Introduction: Although widely prescribed, the benefit of thyroid hormone replacement in subclinical hypothyroidism (SHypo) is unclear. We performed a systematic review and meta-analysis of randomized controlled trails (RCTs) to assess the impact of thyroid hormone therapy on clinical outcomes.Methods: We followed the PRISMA guidelines and registered the study protocol on PROSPERO (CRD42017055536). We searched PubMed, Embase, Web of Science, COCHRANE Libr...

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Thyroid hormone replacement therapy for subclinical hypothyroidism in adults: systematic review and meta-analysis of randomized-controlled trials

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